› 8fnv

Electron Microscopy
2.11Å resolution

Structure of RdrB from Escherichia coli RADAR defense system

Released:
DOI: 10.2210/pdb8fnv/pdb
PDB entry 8fnv coloured by chain, front view.
PDB entry 8fnv coloured by chain, side view.
PDB entry 8fnv coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Duncan-Lowey B, Tal N, Johnson AG, Rawson S, Mayer ML, Doron S, Millman A, Melamed S, Fedorenko T, Kacen A, Brandis A, Mehlman T, Amitai G, Sorek R, Kranzusch PJ
OpenAccess logo Cell (2023)
PMID: 36764290
Related structures: EMD-29327

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-237436 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine deaminase Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 798 amino acids
Theoretical weight: 92.13 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli

Ligands and Environments

1 bound ligand:
Ligand ZN 12 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.11Å
Relevant EMDB volumes: EMD-29327
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The highly diverse antiphage defence systems of bacteria.
Georjon et al. (2023)
4 more

1 mention without citation

Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Duncan-Lowey et al. (2023)