Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
DNA polymerase alpha:primase complex (preferred)
PDBe Complex ID:
PDB-CPX-233976 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
DNA primase large subunit
Molecule details ›
Chain: B
Length: 528 amino acids
Theoretical weight: 62.35 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Eukaryotic and archaeal DNA primase, large subunit
Length: 528 amino acids
Theoretical weight: 62.35 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
P20457 (Residues: 1-528; Coverage: 100%)
Sequence domains: Eukaryotic and archaeal DNA primase, large subunit
DNA primase small subunit
Molecule details ›
Chain: A
Length: 409 amino acids
Theoretical weight: 47.76 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: DNA primase small subunit
Length: 409 amino acids
Theoretical weight: 47.76 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P10363 (Residues: 1-409; Coverage: 100%)
Sequence domains: DNA primase small subunit
DNA polymerase alpha subunit B
Molecule details ›
Chain: C
Length: 705 amino acids
Theoretical weight: 78.87 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 705 amino acids
Theoretical weight: 78.87 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P38121 (Residues: 1-705; Coverage: 100%)
Sequence domains:
DNA polymerase alpha catalytic subunit A
Molecule details ›
