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LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)

Source organism: Rattus norvegicus
Biochemical function: signaling receptor activity
Biological process: monoatomic ion transport
Cellular component: membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00060
Domain description: Ligand-gated ion channel
Occurring in:
  1. Glutamate receptor 2
The deposited structure of PDB entry 8fpv contains 4 copies of Pfam domain PF00060 (Ligand-gated ion channel) in Glutamate receptor 2. Showing 1 copy in chain B.

PF10613
Domain description: Ligated ion channel L-glutamate- and glycine-binding site
Occurring in:
  1. Glutamate receptor 2
The deposited structure of PDB entry 8fpv contains 4 copies of Pfam domain PF10613 (Ligated ion channel L-glutamate- and glycine-binding site) in Glutamate receptor 2. Showing 1 copy in chain B.

PF01094
Domain description: Receptor family ligand binding region
Occurring in:
  1. Glutamate receptor 2
The deposited structure of PDB entry 8fpv contains 4 copies of Pfam domain PF01094 (Receptor family ligand binding region) in Glutamate receptor 2. Showing 1 copy in chain B (this domain is out of the observed residue ranges!).

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