› 8ft5

X-ray diffraction
3.8Å resolution

Crystal structure of LeuT soaked with Crown-5

Released:
DOI: 10.2210/pdb8ft5/pdb
PDB entry 8ft5 coloured by chain, front view.
PDB entry 8ft5 coloured by chain, side view.
PDB entry 8ft5 coloured by chain, top view.
Source organism: Aquifex aeolicus
Entry authors: Karasawa A, Liu H, Quick M, Hendrickson AH, Liu Q

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130575 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Na(+):neurotransmitter symporter (Snf family) Chain: A
Molecule details ›
Chain: A
Length: 520 amino acids
Theoretical weight: 58.32 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O67854 (Residues: 1-513; Coverage: 100%)
Gene names: aq_2077, snf
Sequence domains: Sodium:neurotransmitter symporter family

Ligands and Environments

3 bound ligands:
Ligand NA 2 x NA
Ligand CL 1 x CL
Ligand LEU 1 x LEU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS-II BEAMLINE 17-ID-2
Spacegroup: C2
Unit cell:
a: 86.442Å b: 87.383Å c: 80.798Å
α: 90° β: 95.062° γ: 90°
R-values:
R R work R free
0.275 0.271 0.313
Expression system: Escherichia coli

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