Function and Biology Details
Reaction catalysed:
Preferred amino acids around the cleavage site can be denoted BBBBxHx-|-H, in which B denotes Arg or Lys, H denotes a hydrophobic amino acid, and x is any amino acid. The only known protein substrates are mitogen-activated protein (MAP) kinase kinases.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-238099 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Baculoviral IAP repeat-containing protein 1
Molecule details ›
Chain: A
Length: 1409 amino acids
Theoretical weight: 160.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 1409 amino acids
Theoretical weight: 160.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q13075 (Residues: 1-1403; Coverage: 100%)
Sequence domains:
NLR family CARD domain-containing protein 4
Molecule details ›
Chain: B
Length: 1030 amino acids
Theoretical weight: 116.94 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 1030 amino acids
Theoretical weight: 116.94 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q9NPP4 (Residues: 1-1024; Coverage: 100%)
Sequence domains:
Lethal factor; Type III secretion system protein
Molecule details ›
Chain: U
Length: 374 amino acids
Theoretical weight: 42.83 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 374 amino acids
Theoretical weight: 42.83 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P15917 (Residues: 34-296, 346-346; Coverage: 34%)
- Canonical: Q63K18 (Residues: 2-33, 35-89; Coverage: 98%)
Sequence domains:
