Function and Biology

Buspirone-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex

Source organisms:
Biochemical function: protein binding
Biological process: G protein-coupled receptor signaling pathway
Cellular component: plasma membrane

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
The deposited structure of PDB entry 8fyx contains 7 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. Showing 7 copies in chain B.

PF00001
Domain description: 7 transmembrane receptor (rhodopsin family)
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562
The deposited structure of PDB entry 8fyx contains 1 copy of Pfam domain PF00001 (7 transmembrane receptor (rhodopsin family)) in 5-hydroxytryptamine receptor 1A. Showing 1 copy in chain D [auth R].

PF07361
Domain description: Cytochrome b562
Occurring in:
  1. 5-hydroxytryptamine receptor 1A; Soluble cytochrome b562

PF00631
Domain description: GGL domain
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
The deposited structure of PDB entry 8fyx contains 1 copy of Pfam domain PF00631 (GGL domain) in Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2. Showing 1 copy in chain C [auth G].

PF00503
Domain description: G-protein alpha subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
The deposited structure of PDB entry 8fyx contains 1 copy of Pfam domain PF00503 (G-protein alpha subunit) in Guanine nucleotide-binding protein G(i) subunit alpha-1. Showing 1 copy in chain A.