› 8fzm

X-ray diffraction
3Å resolution

Human importin alpha 3 in complex with Bimax2 peptide

Released:
DOI: 10.2210/pdb8fzm/pdb
PDB entry 8fzm coloured by chain, front view.
PDB entry 8fzm coloured by chain, side view.
PDB entry 8fzm coloured by chain, top view.
Source organisms:
Entry authors: Donnelly CM, Forwood JK

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126376 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-3 Chains: A, C
Molecule details ›
Chains: A, C
Length: 459 amino acids
Theoretical weight: 50.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00629 (Residues: 64-521; Coverage: 88%)
Gene names: KPNA4, QIP1
Sequence domains:
Bimax2 Chains: B, D
Molecule details ›
Chains: B, D
Length: 27 amino acids
Theoretical weight: 3.66 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P1
Unit cell:
a: 48.209Å b: 91.61Å c: 99.219Å
α: 79.33° β: 81.04° γ: 89.96°
R-values:
R R work R free
0.231 0.23 0.26
Expression system: Escherichia coli BL21(DE3)

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