8g30

Electron Microscopy
3.1Å resolution

Function and Biology Details

Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-269345 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (7 distinct):
FNI19 Fab heavy chain Chains: E, G, H, J
Molecule details ›
Chains: E, G, H, J
Length: 231 amino acids
Theoretical weight: 24.69 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
FNI19 Fab light chain Chains: F, I, K, L
Molecule details ›
Chains: F, I, K, L
Length: 215 amino acids
Theoretical weight: 23.55 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Neuraminidase Chains: M, N, O, P

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-29686
Expression systems:
  • Cricetulus griseus
  • Homo sapiens