8g7l

Electron Microscopy
2.5Å resolution

ATP-bound mtHsp60 V72I

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O + a folded polypeptide = ADP + phosphate + an unfolded polypeptide
Cellular component:

Structure analysis Details

Assembly composition:
homo tetradecamer (preferred)
PDBe Complex ID:
PDB-CPX-536150 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
60 kDa heat shock protein, mitochondrial Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Length: 550 amino acids
Theoretical weight: 58.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10809 (Residues: 27-573; Coverage: 96%)
Gene names: HSP60, HSPD1
Sequence domains: TCP-1/cpn60 chaperonin family

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.5Å
Relevant EMDB volumes: EMD-29815
Expression system: Escherichia coli