› 8g9x

Electron Microscopy
4.46Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-274670 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (7 distinct):
Transmembrane protein gp41 Chains: B, D, O
Molecule details ›
Chains: B, D, O
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
Transmembrane protein gp41 Chains: E, G, P
Molecule details ›
Chains: E, G, P
Length: 481 amino acids
Theoretical weight: 54.09 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-510; Coverage: 56%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
vFP49.02 heavy chain Chain: H
vFP49.02 light chain Chain: L

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
1 bound ligand:
Ligand NAG 15 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.46Å
Relevant EMDB volumes: EMD-29881
Expression system: Homo sapiens

Quick links

Citations

3 review citations

'Immunization during ART and ATI for HIV-1 vaccine discovery/development'.
Stamatatos L. (2023)
2 more

1 mention without citation

Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
Sastry et al. (2023)