› 8gb8

X-ray diffraction
2.3Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-225330 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike protein S1 Chain: E
Molecule details ›
Chain: E
Length: 231 amino acids
Theoretical weight: 26.26 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P0DTC2 (Residues: 319-541; Coverage: 18%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
20A7 Heavy chain Chain: H
Molecule details ›
Chain: H
Length: 224 amino acids
Theoretical weight: 23.83 KDa
Source organism: Macaca mulatta
Expression system: Mus musculus
20A7 Light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.2 KDa
Source organism: Macaca mulatta
Expression system: Mus musculus

Ligands and Environments

5 bound ligands:
Ligand NAG 1 x NAG
Ligand EDO 3 x EDO
Ligand GOL 1 x GOL
Ligand GLY 1 x GLY
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-1
Spacegroup: P212121
Unit cell:
a: 44.544Å b: 132.184Å c: 170.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.2 0.228
Expression systems:
  • Trichoplusia ni
  • Mus musculus

Quick links

Citations

1 review citation

In search of a pan-coronavirus vaccine: next-generation vaccine design and immune mechanisms.
Cankat et al. (2024)
2 other articles