› 8gdg

Solution NMR

Solution structure of the Neutrophil Serine Protease Inhibitor, EapH2

Released:
DOI: 10.2210/pdb8gdg/pdb
PDB entry 8gdg coloured by chain, ensemble of 20 models, front view.
PDB entry 8gdg coloured by chain, ensemble of 20 models, side view.
PDB entry 8gdg coloured by chain, ensemble of 20 models, top view.
Source organism: Staphylococcus aureus
Primary publication:
Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2.
Mishra N, Herdendorf TJ, Prakash O, Geisbrecht BV
OpenAccess logo J Biol Chem 104878 (2023)
PMID: 37269950

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101978 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MAP domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.12 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0H3JUK5 (Residues: 31-144; Coverage: 79%)
Gene name: SAV0981
Sequence domains: MAP domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 87%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 mention without citation

Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2.
Mishra et al. (2023)