8go9

Electron Microscopy
3.35Å resolution

Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Atypical chemokine receptor 2, ACKR2 (D6R)

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-271480 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Beta-arrestin-2 Chains: A, F
Molecule details ›
Chains: A, F
Length: 420 amino acids
Theoretical weight: 47.22 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P32120 (Residues: 1-420; Coverage: 100%)
Gene name: ARRB2
Sequence domains:
Fab30 Heavy Chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 237 amino acids
Theoretical weight: 25.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Fab30 Light Chain Chains: C, E
Molecule details ›
Chains: C, E
Length: 215 amino acids
Theoretical weight: 23.44 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Atypical chemokine receptor 2 Chains: G, H
Molecule details ›
Chains: G, H
Length: 18 amino acids
Theoretical weight: 2.35 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O00590 (Residues: 338-355; Coverage: 5%)
Gene names: ACKR2, CCBP2, CCR10, CMKBR9, D6

Ligands and Environments

No bound ligands
2 modified residues:

Experiments and Validation Details

Entry percentile scores
Resolution: 3.35Å
Relevant EMDB volumes: EMD-34174
Expression systems:
  • Escherichia coli
  • Not provided