› 8gs4

Electron Microscopy
3.5Å resolution

Cryo-EM structure of human Neuroligin 2

Released:
DOI: 10.2210/pdb8gs4/pdb
PDB entry 8gs4 coloured by chain, front view.
PDB entry 8gs4 coloured by chain, side view.
PDB entry 8gs4 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.
Zhang Z, Hou M, Ou H, Wang D, Li Z, Zhang H, Lu J
Front Endocrinol (Lausanne) 13 1067529 (2022)
PMID: 36479216
Related structures: EMD-34220

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185541 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuroligin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 835 amino acids
Theoretical weight: 90.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8NFZ4 (Residues: 1-835; Coverage: 100%)
Gene names: KIAA1366, NLGN2
Sequence domains: Carboxylesterase family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-34220
Expression system: Homo sapiens

Quick links

Citations

1 review citation

The enteric nervous system deficits in autism spectrum disorder.
Wang et al. (2023)
1 other article

1 mention without citation

Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.
Zhang et al. (2022)