› 8gyk

Electron Microscopy
3.14Å resolution

CryoEM structure of the RAD51_ADP filament

Released:
DOI: 10.2210/pdb8gyk/pdb
PDB entry 8gyk coloured by chain, front view.
PDB entry 8gyk coloured by chain, side view.
PDB entry 8gyk coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A RAD51-ADP double filament structure unveils the mechanism of filament dynamics in homologous recombination.
Luo SC, Yeh MC, Lien YH, Yeh HY, Siao HL, Tu IP, Chi P, Ho MC
OpenAccess logo Nat Commun 14 4993 (2023)
PMID: 37591853
Related structures: EMD-34372

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-554883 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair protein RAD51 homolog 1 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 339 amino acids
Theoretical weight: 37.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q06609 (Residues: 1-339; Coverage: 100%)
Gene names: RAD51, RAD51A, RECA
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand ADP 8 x ADP
Ligand MG 8 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.14Å
Relevant EMDB volumes: EMD-34372
Expression system: Escherichia coli

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