› 8gyt

Electron Microscopy
3.68Å resolution

Cryo-EM structure of human Pannexin-3 R36S/F40R variant in pre-open state.

Released:
DOI: 10.2210/pdb8gyt/pdb
PDB entry 8gyt coloured by chain, front view.
PDB entry 8gyt coloured by chain, side view.
PDB entry 8gyt coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Cong Y, Jin X, Kong F, Wu T, Yan C
Related structures: EMD-34377

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-572564 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pannexin-3 Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 392 amino acids
Theoretical weight: 44.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q96QZ0 (Residues: 1-392; Coverage: 100%)
Gene name: PANX3
Sequence domains: Innexin

Ligands and Environments

1 bound ligand:
Ligand NAG 7 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.68Å
Relevant EMDB volumes: EMD-34377
Expression system: Homo sapiens

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