8h01

Electron Microscopy
3.7Å resolution

SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in class 2 conformation

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-210431 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1286 amino acids
Theoretical weight: 142.62 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-214, 215-1208; Coverage: 94%)
Gene names: 2, S
Sequence domains:
rabbit monoclonal antibody 1H1 Fab light chain Chains: D, F, H
Molecule details ›
Chains: D, F, H
Length: 111 amino acids
Theoretical weight: 11.74 KDa
Source organism: Oryctolagus cuniculus
Expression system: Homo sapiens
rabbit monoclonal antibody 1H1 Fab heavy chain Chains: E, G, I
Molecule details ›
Chains: E, G, I
Length: 122 amino acids
Theoretical weight: 12.86 KDa
Source organism: Oryctolagus cuniculus
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-34408
Expression system: Homo sapiens