8h0q

Electron Microscopy
3.3Å resolution

Structure of the GRP14-27-GRPR-Gq complex

Released:
Source organisms:
Related structures: EMD-34414

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-272387 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Gastrin-releasing peptide receptor Chain: R
Molecule details ›
Chain: R
Length: 384 amino acids
Theoretical weight: 43.26 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Neuromedin-C Chain: L
Molecule details ›
Chain: L
Length: 9 amino acids
Theoretical weight: 1.07 KDa
Source organism: Homo sapiens
Expression system: Not provided
Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Chain: A
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
scFv16 Chain: E
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: G

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-34414
Expression systems:
  • Trichoplusia ni
  • Not provided