› 8h86

Electron Microscopy
2.56Å resolution

Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR1 in lipid nanodisc

Released:
DOI: 10.2210/pdb8h86/pdb
PDB entry 8h86 coloured by chain, front view.
PDB entry 8h86 coloured by chain, side view.
PDB entry 8h86 coloured by chain, top view.
Source organism: Hyphochytrium catenoides
Primary publication:
Structural basis for ion selectivity in potassium-selective channelrhodopsins.
Tajima S, Kim YS, Fukuda M, Jo Y, Wang PY, Paggi JM, Inoue M, Byrne EFX, Kishi KE, Nakamura S, Ramakrishnan C, Takaramoto S, Nagata T, Konno M, Sugiura M, Katayama K, Matsui TE, Yamashita K, Kim S, Ikeda H, Kim J, Kandori H, Dror RO, Inoue K, Deisseroth K, Kato HE
OpenAccess logo Cell 186 4325-4344.e26 (2023)
PMID: 37652010
Related structures: EMD-34530

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-227806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HcKCR1 Chain: A
Molecule details ›
Chain: A
Length: 273 amino acids
Theoretical weight: 31.4 KDa
Source organism: Hyphochytrium catenoides
Expression system: Spodoptera frugiperda

Ligands and Environments

3 bound ligands:
Ligand RET 1 x RET
Ligand PSC 10 x PSC
Ligand PLM 5 x PLM
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.56Å
Relevant EMDB volumes: EMD-34530
Expression system: Spodoptera frugiperda

Quick links

Citations

1 review citation

Na+ Binding and Transport: Insights from Light-Driven Na+-Pumping Rhodopsin.
Yang et al. (2023)
2 other articles