8hc8

Electron Microscopy
3.95Å resolution

SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with YB13-292 Fab, focused refinement of Fab region

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-225335 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike protein S1 Chain: C
Molecule details ›
Chain: C
Length: 186 amino acids
Theoretical weight: 21.33 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 332-517; Coverage: 15%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Heavy chain of YB13-292 Fab Chain: H
Molecule details ›
Chain: H
Length: 238 amino acids
Theoretical weight: 25.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Light chain of YB13-292 Fab Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 23.98 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.95Å
Relevant EMDB volumes: EMD-34655
Expression system: Homo sapiens