› 8hf6

Electron Microscopy
3.1Å resolution

Cryo-EM structure of nucleotide-bound ComA E647Q mutant

Released:
DOI: 10.2210/pdb8hf6/pdb
PDB entry 8hf6 coloured by chain, front view.
PDB entry 8hf6 coloured by chain, side view.
PDB entry 8hf6 coloured by chain, top view.
Source organism: Streptococcus pneumoniae D39
Primary publication:
Structural basis of peptide secretion for Quorum sensing by ComA.
Yu L, Xu X, Chua WZ, Feng H, Ser Z, Shao K, Shi J, Wang Y, Li Z, Sobota RM, Sham LT, Luo M
OpenAccess logo Nat Commun 14 7178 (2023)
PMID: 37935699
Related structures: EMD-34714

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-268651 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Competence factor transporting ATP-binding/permease protein ComA Chains: A, B
Molecule details ›
Chains: A, B
Length: 717 amino acids
Theoretical weight: 80.43 KDa
Source organism: Streptococcus pneumoniae D39
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H2ZPI8 (Residues: 1-717; Coverage: 100%)
Gene names: SPD_0049, comA
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ATP 2 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-34714
Expression system: Escherichia coli

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