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Cryo-EM structure of yeast Erf2/Erf4 complex

Source organism: Saccharomyces cerevisiae S288C
Biochemical function: palmitoyltransferase activity
Biological process: protein targeting to membrane
Cellular component: endoplasmic reticulum palmitoyltransferase complex

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EC 2.3.1.225: Protein S-acyltransferase

Reaction catalysed:
Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA
Systematic name:
Palmitoyl-CoA:[protein]-L-cysteine S-palmitoyltransferase
Alternative Name(s):
  • DHHC palmitoyl transferase
  • G-protein palmitoyltransferase
  • S-protein acyltransferase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF10256
Domain description: Golgin subfamily A member 7/ERF4 family
Occurring in:
  1. Ras modification protein ERF4
The deposited structure of PDB entry 8hfc contains 1 copy of Pfam domain PF10256 (Golgin subfamily A member 7/ERF4 family) in Ras modification protein ERF4. Showing 1 copy in chain B.

PF01529
Domain description: DHHC palmitoyltransferase
Occurring in:
  1. Palmitoyltransferase ERF2
The deposited structure of PDB entry 8hfc contains 1 copy of Pfam domain PF01529 (DHHC palmitoyltransferase) in Palmitoyltransferase ERF2. Showing 1 copy in chain A.

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