› 8hgz

X-ray diffraction
1.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134210 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, E, I, M
Molecule details ›
Chains: A, E, I, M
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Gene name: INS
Insulin B chain Chains: B, F, J, N
Molecule details ›
Chains: B, F, J, N
Length: 29 amino acids
Theoretical weight: 3.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01308 (Residues: 25-53; Coverage: 34%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family

Ligands and Environments

4 bound ligands:
Ligand IPH 5 x IPH
Ligand ZN 4 x ZN
Ligand CL 4 x CL
Ligand MYR 4 x MYR
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU PhotonJet-R
Spacegroup: R3
Unit cell:
a: 78.885Å b: 78.885Å c: 79.272Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.218 0.258
Expression system: Escherichia coli

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