› 8hia

Electron Microscopy
4.9Å resolution

Structure of transforming growth factor beta induced protein (TGFBIp) G623R fibril

Released:
DOI: 10.2210/pdb8hia/pdb
PDB entry 8hia coloured by chain, front view.
PDB entry 8hia coloured by chain, side view.
PDB entry 8hia coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Release of frustration drives corneal amyloid disaggregation by brain chaperone.
Low JYK, Shi X, Anandalakshmi V, Neo D, Peh GSL, Koh SK, Zhou L, Abdul Rahim MK, Boo K, Lee J, Mohanram H, Alag R, Mu Y, Mehta JS, Pervushin K
OpenAccess logo Commun Biol 6 348 (2023)
PMID: 36997596
Related structures: EMD-34813

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo icosamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-222582 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transforming growth factor-beta-induced protein ig-h3 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Length: 23 amino acids
Theoretical weight: 2.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15582 (Residues: 611-633; Coverage: 4%)
Gene names: BIGH3, TGFBI

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.9Å
Relevant EMDB volumes: EMD-34813
Expression system: Escherichia coli

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