Function and Biology

Crystal structure of p53/BCL2 fusion complex (complex 1)

Source organism: Homo sapiens
Biochemical function: DNA-binding transcription factor activity
Biological process: regulation of apoptotic process
Cellular component: nucleus

Sequence families

Pfam Protein families (Pfam)
PF00452
Domain description: Apoptosis regulator proteins, Bcl-2 family
Occurring in:
  1. Apoptosis regulator Bcl-2
The deposited structure of PDB entry 8hll contains 1 copy of Pfam domain PF00452 (Apoptosis regulator proteins, Bcl-2 family) in Apoptosis regulator Bcl-2. Showing 1 copy in chain B.

PF02180
Domain description: Bcl-2 homology region 4
Occurring in:
  1. Apoptosis regulator Bcl-2
The deposited structure of PDB entry 8hll contains 1 copy of Pfam domain PF02180 (Bcl-2 homology region 4) in Apoptosis regulator Bcl-2. Showing 1 copy in chain B.

PF00870
Domain description: P53 DNA-binding domain
Occurring in:
  1. Cellular tumor antigen p53
The deposited structure of PDB entry 8hll contains 1 copy of Pfam domain PF00870 (P53 DNA-binding domain) in Cellular tumor antigen p53. Showing 1 copy in chain A.