Function and Biology Details
Reactions catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-498594 (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (5 distinct):
DNA polymerase
Molecule details ›
Chain: A
Length: 1029 amino acids
Theoretical weight: 120.04 KDa
Source organism: Monkeypox virus
Expression system: Insect expression vector pBlueBachsGCA1
UniProt:
Sequence domains:
Length: 1029 amino acids
Theoretical weight: 120.04 KDa
Source organism: Monkeypox virus
Expression system: Insect expression vector pBlueBachsGCA1
UniProt:
- Canonical:
A0A7H0DN44 (Residues: 1-1006; Coverage: 100%)
Sequence domains:
DNA polymerase processivity factor component OPG148
Molecule details ›
Chain: C
Length: 426 amino acids
Theoretical weight: 49.2 KDa
Source organism: Monkeypox virus
Expression system: Insect expression vector pBlueBachsGCA1
UniProt:
Sequence domains: Chordopoxvirus A20R protein
Length: 426 amino acids
Theoretical weight: 49.2 KDa
Source organism: Monkeypox virus
Expression system: Insect expression vector pBlueBachsGCA1
UniProt:
- Canonical: A0A7H0DNC0 (Residues: 1-426; Coverage: 100%)
Sequence domains: Chordopoxvirus A20R protein
Uracil-DNA glycosylase
Molecule details ›
Chain: B
Length: 241 amino acids
Theoretical weight: 27.88 KDa
Source organism: Monkeypox virus
Expression system: Insect expression vector pBlueBachsGCA1
UniProt:
Length: 241 amino acids
Theoretical weight: 27.88 KDa
Source organism: Monkeypox virus
Expression system: Insect expression vector pBlueBachsGCA1
UniProt:
- Canonical: M1LL92 (Residues: 1-218; Coverage: 100%)
