8hpv

Electron Microscopy
2.65Å resolution

Cryo-EM structure of SARS-CoV-2 Omicron Prototype S-trimer in complex with fab L4.65 and L5.34

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero pentadecamer (preferred)
PDBe Complex ID:
PDB-CPX-279759 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (6 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1134 amino acids
Theoretical weight: 125.61 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 14-1147; Coverage: 90%)
Gene names: 2, S
Sequence domains:
fab L5.34 Chains: E, M, R
Molecule details ›
Chains: E, M, R
Length: 225 amino acids
Theoretical weight: 23.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
fab L5.34 Chains: F, N, S
fab L4.65 Chains: H, I, P
fab L4.65 Chains: J, L, Q

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.65Å
Relevant EMDB volumes: EMD-34945
Expression system: Homo sapiens