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The complex structure of COPI cargo sorting module with TAT-WDM peptide

X-ray diffraction
1.538Å resolution
PDB entry 8hqx coloured by chain, front view.
PDB entry 8hqx coloured by chain, side view.
PDB entry 8hqx coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Coatomer subunit beta' and peptide
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Multimeric state: hetero dimer
Accessible surface area: 11452.04 Å2
Buried surface area: 779.43 Å2
Dissociation area: 389.71 Å2
Dissociation energy (ΔGdiss): -1.87 kcal/mol
Dissociation entropy (TΔSdiss): 5.75 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-242318

Macromolecules

Coatomer subunit beta'
Chain: A
Length: 301 amino acids
Theoretical weight: 34.29 KDa
Source organism: Saccharomyces cerevisiae YJM789
Expression system: Escherichia coli
UniProt:
  • Canonical: P41811 (Residues: 1-301; Coverage: 34%)
Gene names: G2827, SEC27, YGL137W
Pfam: WD domain, G-beta repeat
Coatomer subunit beta' in PDB entry 8hqx, assembly 1, front view.
Coatomer subunit beta' in PDB entry 8hqx, assembly 1, side view.
Coatomer subunit beta' in PDB entry 8hqx, assembly 1, top view.
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TAT-WDM KxKxx motif
Chain: B
Length: 6 amino acids
Theoretical weight: 679 Da
Source organism: Homo sapiens
Expression system: Not provided
TAT-WDM KxKxx motif in PDB entry 8hqx, assembly 1, front view.
TAT-WDM KxKxx motif in PDB entry 8hqx, assembly 1, side view.
TAT-WDM KxKxx motif in PDB entry 8hqx, assembly 1, top view.
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