› 8hrl

Electron Microscopy
2.8Å resolution

SARS-CoV-2 Delta S-RBD-ACE2

Released:
DOI: 10.2210/pdb8hrl/pdb
PDB entry 8hrl coloured by chain, front view.
PDB entry 8hrl coloured by chain, side view.
PDB entry 8hrl coloured by chain, top view.
Source organisms:
Entry authors: Xu J, Meng F, Liu N, Wang HW
Related structures: EMD-34977

Function and Biology Details

Reaction catalysed: 
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144194 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Processed angiotensin-converting enzyme 2 Chain: A
Molecule details ›
Chain: A
Length: 597 amino acids
Theoretical weight: 69.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9BYF1 (Residues: 19-615; Coverage: 76%)
Gene names: ACE2, UNQ868/PRO1885
Sequence domains: Angiotensin-converting enzyme
Spike protein S1 Chain: E
Molecule details ›
Chain: E
Length: 194 amino acids
Theoretical weight: 21.85 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 333-526; Coverage: 15%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.8Å
Relevant EMDB volumes: EMD-34977
Expression system: Homo sapiens

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