Function and Biology

Cryo-EM structure of Eaf3 CHD in complex with nucleosome

Source organisms:
Biochemical function: protein heterodimerization activity
Biological process: nucleosome assembly
Cellular component: nucleus

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00125
Domain description: Core histone H2A/H2B/H3/H4
Occurring in:
  1. Histone H3.2
  2. Histone H2A type 1
  3. Histone H2B 1.1
The deposited structure of PDB entry 8hxz contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H3. Showing 1 copy in chain A.
The deposited structure of PDB entry 8hxz contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2A. Showing 1 copy in chain C.
The deposited structure of PDB entry 8hxz contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2B. Showing 1 copy in chain D.

PF16211
Domain description: C-terminus of histone H2A
Occurring in:
  1. Histone H2A type 1
The deposited structure of PDB entry 8hxz contains 2 copies of Pfam domain PF16211 (C-terminus of histone H2A) in Histone H2A. Showing 1 copy in chain C.

PF15511
Domain description: Centromere kinetochore component CENP-T histone fold
Occurring in:
  1. Histone H4
The deposited structure of PDB entry 8hxz contains 2 copies of Pfam domain PF15511 (Centromere kinetochore component CENP-T histone fold) in Histone H4. Showing 1 copy in chain B.

PF05712
Domain description: MRG
Occurring in:
  1. Chromatin modification-related protein EAF3
The deposited structure of PDB entry 8hxz contains 1 copy of Pfam domain PF05712 (MRG) in Chromatin modification-related protein EAF3. Showing 1 copy in chain K [auth M] (this domain is out of the observed residue ranges!).

PF22732
Domain description: MSL3 chromodomain-like
Occurring in:
  1. Chromatin modification-related protein EAF3

PF11717
Domain description: RNA binding activity-knot of a chromodomain
Occurring in:
  1. Chromatin modification-related protein EAF3
The deposited structure of PDB entry 8hxz contains 1 copy of Pfam domain PF11717 (RNA binding activity-knot of a chromodomain ) in Chromatin modification-related protein EAF3. Showing 1 copy in chain K [auth M].