› 8i0b

X-ray diffraction
1.73Å resolution

The crystal structure of human glutamate receptor 2 in complex with LT-102

Released:
DOI: 10.2210/pdb8i0b/pdb
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PDB entry 8i0b coloured by chain, front view.
PDB entry 8i0b coloured by chain, side view.
PDB entry 8i0b coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Qi XY, Wu CY

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154589 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 301 amino acids
Theoretical weight: 33.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P42262 (Residues: 413-527, 653-834; Coverage: 35%)
Gene names: GLUR2, GRIA2, GluA2
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand SO4 4 x SO4
Ligand NXO 1 x NXO
Ligand NA 1 x NA
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL19U1
Unit cell:
a: 121.4Å b: 47.104Å c: 98.413Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.221 0.278
Expression system: Escherichia coli

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