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The cryo-EM structure of human pre-Bact complex

Source organism: Homo sapiens
Biochemical function: protein binding
Biological process: mRNA processing
Cellular component: nucleoplasm

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EC 3.6.4.13: RNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (RNA helix unwinding)
Alternative Name(s):
  • CSFV NS3 helicase
  • DBP2
  • DDX17
  • DDX25
  • DDX3
  • DDX3X
  • DDX3Y
  • DDX4
  • DDX5
  • DEAD-box RNA helicase
  • DEAD-box protein DED1
  • DEAH-box RNA helicase
  • DEAH-box protein 2
  • DED1
  • DbpA
  • Dex(H/D) RNA helicase
  • EIF4A helicase
  • EhDEAD1
  • EhDEAD1 RNA helicase
  • GRTH/DDX25
  • KOKV helicase
  • Mtr4p
  • NPH-II
  • Nonstructural protein 3 helicase
  • RHA
  • RNA helicase A
  • RNA helicase DDX3
  • RNA helicase Hera
  • RNA-dependent ATPase
  • TGBp1 NTPase/helicase domain
  • VRH1

EC 5.2.1.8: Peptidylprolyl isomerase

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0)
Systematic name:
Peptidylproline cis-trans-isomerase
Alternative Name(s):
  • Cyclophilin
  • PPIase
  • Peptide bond isomerase
  • Peptidyl-prolyl cis-trans isomerase
  • Peptidylprolyl cis-trans isomerase
  • Rotamase

EC 2.3.2.27: RING-type E3 ubiquitin transferase

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Systematic name:
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein]-L-lysine ubiquitin transferase (isopeptide bond-forming; RING-type)
Alternative Name(s):
  • RING E3 ligase
  • Ubiquitin transferase RING E3

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF01423
Domain description: LSM domain
Occurring in:
  1. Small nuclear ribonucleoprotein-associated proteins B and B'
  2. Small nuclear ribonucleoprotein Sm D1
  3. Small nuclear ribonucleoprotein Sm D2
  4. Small nuclear ribonucleoprotein F
  5. Small nuclear ribonucleoprotein E
  6. Small nuclear ribonucleoprotein G
  7. Small nuclear ribonucleoprotein Sm D3
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein Sm D2. Showing 1 copy in chain UA [auth c].
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein F. Showing 1 copy in chain VA [auth d].
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein-associated proteins B and B'. Showing 1 copy in chain SA [auth a].
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein Sm D3. Showing 1 copy in chain CA [auth l].
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein G. Showing 1 copy in chain XA [auth f].
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein E. Showing 1 copy in chain EA [auth j].
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein Sm D1. Showing 1 copy in chain TA [auth b].

PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. U5 small nuclear ribonucleoprotein 40 kDa protein
  2. Pleiotropic regulator 1
The deposited structure of PDB entry 8i0p contains 7 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in U5 small nuclear ribonucleoprotein 40 kDa protein. Showing 7 copies in chain E.
The deposited structure of PDB entry 8i0p contains 7 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Pleiotropic regulator 1. Showing 7 copies in chain R [auth T].

PF00076
Domain description: RNA recognition motif
Occurring in:
  1. Splicing factor 3B subunit 4
  2. Splicing factor 3B subunit 6
  3. Pre-mRNA-splicing factor RBM22
  4. RNA-binding motif protein, X-linked 2
  5. U2 small nuclear ribonucleoprotein B''
  6. Peptidyl-prolyl cis-trans isomerase E
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00076 (RNA recognition motif) in Pre-mRNA-splicing factor RBM22. Showing 1 copy in chain N [auth O].
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00076 (RNA recognition motif) in RNA-binding motif protein, X-linked 2. Showing 1 copy in chain T [auth Y].
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF00076 (RNA recognition motif) in U2 small nuclear ribonucleoprotein B''. Showing 2 copies in chain Y [auth p].
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF00076 (RNA recognition motif) in Splicing factor 3B subunit 4. Showing 2 copies in chain JA [auth 4].
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00076 (RNA recognition motif) in Splicing factor 3B subunit 6. Showing 1 copy in chain KA [auth 6].
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00076 (RNA recognition motif) in Peptidyl-prolyl cis-trans isomerase E. Showing 1 copy in chain PA [auth y].

PF01805
Domain description: Surp module
Occurring in:
  1. Splicing factor 3A subunit 1
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF01805 (Surp module) in Splicing factor 3A subunit 1. Showing 2 copies in chain HA [auth u].

PF13921
Domain description: Myb-like DNA-binding domain
Occurring in:
  1. Cell division cycle 5-like protein
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF13921 (Myb-like DNA-binding domain) in Cell division cycle 5-like protein. Showing 2 copies in chain L.

PF02184
Domain description: HAT (Half-A-TPR) repeat
Occurring in:
  1. Crooked neck-like protein 1
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF02184 (HAT (Half-A-TPR) repeat) in Crooked neck-like protein 1. Showing 2 copies in chain J.

PF13181
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Pre-mRNA-splicing factor SYF1
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF13181 (Tetratricopeptide repeat) in Pre-mRNA-splicing factor SYF1. Showing 2 copies in chain I.

PF02889
Domain description: Sec63 Brl domain
Occurring in:
  1. U5 small nuclear ribonucleoprotein 200 kDa helicase
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF02889 (Sec63 Brl domain) in U5 small nuclear ribonucleoprotein 200 kDa helicase. Showing 2 copies in chain D.

PF00270
Domain description: DEAD/DEAH box helicase
Occurring in:
  1. U5 small nuclear ribonucleoprotein 200 kDa helicase
The deposited structure of PDB entry 8i0p contains 2 copies of Pfam domain PF00270 (DEAD/DEAH box helicase) in U5 small nuclear ribonucleoprotein 200 kDa helicase. Showing 2 copies in chain D.

PF00160
Domain description: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Occurring in:
  1. RING-type E3 ubiquitin-protein ligase PPIL2
  2. Peptidyl-prolyl cis-trans isomerase E
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00160 (Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD) in RING-type E3 ubiquitin-protein ligase PPIL2. Showing 1 copy in chain NA [auth 9].
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00160 (Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD) in Peptidyl-prolyl cis-trans isomerase E. Showing 1 copy in chain PA [auth y] (this domain is out of the observed residue ranges!).

PF11931
Domain description: SF3a60/Prp9 C-terminal
Occurring in:
  1. Splicing factor 3A subunit 3
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF11931 (SF3a60/Prp9 C-terminal) in Splicing factor 3A subunit 3. Showing 1 copy in chain GA [auth w].

PF13297
Domain description: Replication stress response SDE2 C-terminal
Occurring in:
  1. Splicing factor 3A subunit 3
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF13297 (Replication stress response SDE2 C-terminal) in Splicing factor 3A subunit 3. Showing 1 copy in chain GA [auth w].

PF16837
Domain description: Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9
Occurring in:
  1. Splicing factor 3A subunit 3
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF16837 (Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9) in Splicing factor 3A subunit 3. Showing 1 copy in chain GA [auth w].

PF12108
Domain description: Splicing factor SF3a60 binding domain
Occurring in:
  1. Splicing factor 3A subunit 3
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF12108 (Splicing factor SF3a60 binding domain) in Splicing factor 3A subunit 3. Showing 1 copy in chain GA [auth w].

PF16835
Domain description: Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
Occurring in:
  1. Splicing factor 3A subunit 2
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF16835 (Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)) in Splicing factor 3A subunit 2. Showing 1 copy in chain QA [auth v].

PF12874
Domain description: Zinc-finger of C2H2 type
Occurring in:
  1. Splicing factor 3A subunit 2
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF12874 (Zinc-finger of C2H2 type) in Splicing factor 3A subunit 2. Showing 1 copy in chain QA [auth v].

PF00240
Domain description: Ubiquitin family
Occurring in:
  1. Splicing factor 3A subunit 1
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00240 (Ubiquitin family) in Splicing factor 3A subunit 1. Showing 1 copy in chain HA [auth u] (this domain is out of the observed residue ranges!).

PF12230
Domain description: Pre-mRNA splicing factor PRP21 like protein
Occurring in:
  1. Splicing factor 3A subunit 1
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF12230 (Pre-mRNA splicing factor PRP21 like protein) in Splicing factor 3A subunit 1. Showing 1 copy in chain HA [auth u].

PF14580
Domain description: Leucine-rich repeat
Occurring in:
  1. U2 small nuclear ribonucleoprotein A'
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF14580 (Leucine-rich repeat) in U2 small nuclear ribonucleoprotein A'. Showing 1 copy in chain X [auth o].

PF09736
Domain description: Pre-mRNA-splicing factor of RES complex
Occurring in:
  1. BUD13 homolog
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF09736 (Pre-mRNA-splicing factor of RES complex) in BUD13 homolog. Showing 1 copy in chain U [auth Z].

PF00498
Domain description: FHA domain
Occurring in:
  1. Smad nuclear-interacting protein 1
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00498 (FHA domain) in Smad nuclear-interacting protein 1. Showing 1 copy in chain S [auth X].

PF02731
Domain description: SKIP/SNW domain
Occurring in:
  1. SNW domain-containing protein 1
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF02731 (SKIP/SNW domain) in SNW domain-containing protein 1. Showing 1 copy in chain Q [auth R].

PF13087
Domain description: AAA domain
Occurring in:
  1. RNA helicase aquarius
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF13087 (AAA domain) in RNA helicase aquarius. Showing 1 copy in chain P [auth Q].

PF13086
Domain description: AAA domain
Occurring in:
  1. RNA helicase aquarius
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF13086 (AAA domain) in RNA helicase aquarius. Showing 1 copy in chain P [auth Q].

PF21144
Domain description: Intron-binding protein aquarius insert domain
Occurring in:
  1. RNA helicase aquarius
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF21144 (Intron-binding protein aquarius insert domain) in RNA helicase aquarius. Showing 1 copy in chain P [auth Q].

PF21143
Domain description: Intron-binding protein aquarius, beta-barrel
Occurring in:
  1. RNA helicase aquarius
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF21143 (Intron-binding protein aquarius, beta-barrel) in RNA helicase aquarius. Showing 1 copy in chain P [auth Q].

PF16399
Domain description: Intron-binding protein aquarius N-terminal
Occurring in:
  1. RNA helicase aquarius
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF16399 (Intron-binding protein aquarius N-terminal) in RNA helicase aquarius. Showing 1 copy in chain P [auth Q].

PF04889
Domain description: Cwf15/Cwc15 cell cycle control protein
Occurring in:
  1. Spliceosome-associated protein CWC15 homolog
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF04889 (Cwf15/Cwc15 cell cycle control protein) in Spliceosome-associated protein CWC15 homolog. Showing 1 copy in chain O [auth P].

PF21369
Domain description: STL11, N-terminal
Occurring in:
  1. Pre-mRNA-splicing factor RBM22
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF21369 (STL11, N-terminal) in Pre-mRNA-splicing factor RBM22. Showing 1 copy in chain N [auth O].

PF01125
Domain description: Pre-mRNA-splicing factor BUD31
Occurring in:
  1. Protein BUD31 homolog
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF01125 (Pre-mRNA-splicing factor BUD31) in Protein BUD31 homolog. Showing 1 copy in chain M [auth N].

PF11831
Domain description: pre-mRNA splicing factor component
Occurring in:
  1. Cell division cycle 5-like protein
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF11831 (pre-mRNA splicing factor component) in Cell division cycle 5-like protein. Showing 1 copy in chain L (this domain is out of the observed residue ranges!).

PF18131
Domain description: KN17 SH3-like C-terminal domain
Occurring in:
  1. DNA/RNA-binding protein KIN17
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF18131 (KN17 SH3-like C-terminal domain) in DNA/RNA-binding protein KIN17. Showing 1 copy in chain K.

PF10357
Domain description: Domain of Kin17 curved DNA-binding protein
Occurring in:
  1. DNA/RNA-binding protein KIN17
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF10357 (Domain of Kin17 curved DNA-binding protein) in DNA/RNA-binding protein KIN17. Showing 1 copy in chain K.

PF00271
Domain description: Helicase conserved C-terminal domain
Occurring in:
  1. U5 small nuclear ribonucleoprotein 200 kDa helicase
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00271 (Helicase conserved C-terminal domain) in U5 small nuclear ribonucleoprotein 200 kDa helicase. Showing 1 copy in chain D.

PF18149
Domain description: N-terminal helicase PWI domain
Occurring in:
  1. U5 small nuclear ribonucleoprotein 200 kDa helicase
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF18149 (N-terminal helicase PWI domain) in U5 small nuclear ribonucleoprotein 200 kDa helicase. Showing 1 copy in chain D (this domain is out of the observed residue ranges!).

PF21188
Domain description: Pre-mRNA-splicing helicase BRR2 plug domain
Occurring in:
  1. U5 small nuclear ribonucleoprotein 200 kDa helicase
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF21188 (Pre-mRNA-splicing helicase BRR2 plug domain) in U5 small nuclear ribonucleoprotein 200 kDa helicase. Showing 1 copy in chain D (this domain is out of the observed residue ranges!).

PF00679
Domain description: Elongation factor G C-terminus
Occurring in:
  1. 116 kDa U5 small nuclear ribonucleoprotein component
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00679 (Elongation factor G C-terminus) in 116 kDa U5 small nuclear ribonucleoprotein component. Showing 1 copy in chain C.

PF03764
Domain description: Elongation factor G, domain IV
Occurring in:
  1. 116 kDa U5 small nuclear ribonucleoprotein component
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF03764 (Elongation factor G, domain IV) in 116 kDa U5 small nuclear ribonucleoprotein component. Showing 1 copy in chain C.

PF14492
Domain description: Elongation Factor G, domain III
Occurring in:
  1. 116 kDa U5 small nuclear ribonucleoprotein component
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF14492 (Elongation Factor G, domain III) in 116 kDa U5 small nuclear ribonucleoprotein component. Showing 1 copy in chain C.

PF03144
Domain description: Elongation factor Tu domain 2
Occurring in:
  1. 116 kDa U5 small nuclear ribonucleoprotein component
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF03144 (Elongation factor Tu domain 2) in 116 kDa U5 small nuclear ribonucleoprotein component. Showing 1 copy in chain C.

PF00009
Domain description: Elongation factor Tu GTP binding domain
Occurring in:
  1. 116 kDa U5 small nuclear ribonucleoprotein component
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF00009 (Elongation factor Tu GTP binding domain) in 116 kDa U5 small nuclear ribonucleoprotein component. Showing 1 copy in chain C.

PF16004
Domain description: 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
Occurring in:
  1. 116 kDa U5 small nuclear ribonucleoprotein component
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF16004 (116 kDa U5 small nuclear ribonucleoprotein component N-terminus) in 116 kDa U5 small nuclear ribonucleoprotein component. Showing 1 copy in chain C.

PF08084
Domain description: PROCT (NUC072) domain
Occurring in:
  1. Pre-mRNA-processing-splicing factor 8
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF08084 (PROCT (NUC072) domain) in Pre-mRNA-processing-splicing factor 8. Showing 1 copy in chain A.

PF01398
Domain description: JAB1/Mov34/MPN/PAD-1 ubiquitin protease
Occurring in:
  1. Pre-mRNA-processing-splicing factor 8
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF01398 (JAB1/Mov34/MPN/PAD-1 ubiquitin protease) in Pre-mRNA-processing-splicing factor 8. Showing 1 copy in chain A.

PF12134
Domain description: PRP8 domain IV core
Occurring in:
  1. Pre-mRNA-processing-splicing factor 8
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF12134 (PRP8 domain IV core) in Pre-mRNA-processing-splicing factor 8. Showing 1 copy in chain A.

PF10596
Domain description: U6-snRNA interacting domain of PrP8
Occurring in:
  1. Pre-mRNA-processing-splicing factor 8
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF10596 (U6-snRNA interacting domain of PrP8) in Pre-mRNA-processing-splicing factor 8. Showing 1 copy in chain A.

PF10597
Domain description: U5-snRNA binding site 2 of PrP8
Occurring in:
  1. Pre-mRNA-processing-splicing factor 8
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF10597 (U5-snRNA binding site 2 of PrP8) in Pre-mRNA-processing-splicing factor 8. Showing 1 copy in chain A.

PF10598
Domain description: RNA recognition motif of the spliceosomal PrP8
Occurring in:
  1. Pre-mRNA-processing-splicing factor 8
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF10598 (RNA recognition motif of the spliceosomal PrP8) in Pre-mRNA-processing-splicing factor 8. Showing 1 copy in chain A.

PF08083
Domain description: PROCN (NUC071) domain
Occurring in:
  1. Pre-mRNA-processing-splicing factor 8
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF08083 (PROCN (NUC071) domain) in Pre-mRNA-processing-splicing factor 8. Showing 1 copy in chain A.

PF08082
Domain description: PRO8NT (NUC069), PrP8 N-terminal domain
Occurring in:
  1. Pre-mRNA-processing-splicing factor 8
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF08082 (PRO8NT (NUC069), PrP8 N-terminal domain) in Pre-mRNA-processing-splicing factor 8. Showing 1 copy in chain A.

PF01480
Domain description: PWI domain
Occurring in:
  1. Serine/arginine repetitive matrix protein 1
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF01480 (PWI domain) in Serine/arginine repetitive matrix protein 1. Showing 1 copy in chain OA [auth 8].

PF03660
Domain description: PHF5-like protein
Occurring in:
  1. PHD finger-like domain-containing protein 5A
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF03660 (PHF5-like protein) in PHD finger-like domain-containing protein 5A. Showing 1 copy in chain LA [auth 7].

PF07189
Domain description: Splicing factor 3B subunit 10 (SF3b10)
Occurring in:
  1. Splicing factor 3B subunit 5
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF07189 (Splicing factor 3B subunit 10 (SF3b10)) in Splicing factor 3B subunit 5. Showing 1 copy in chain MA [auth 5].

PF03178
Domain description: CPSF A subunit region
Occurring in:
  1. Splicing factor 3B subunit 3
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF03178 (CPSF A subunit region) in Splicing factor 3B subunit 3. Showing 1 copy in chain W [auth 3].

PF10433
Domain description: Mono-functional DNA-alkylating methyl methanesulfonate N-term
Occurring in:
  1. Splicing factor 3B subunit 3
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF10433 (Mono-functional DNA-alkylating methyl methanesulfonate N-term) in Splicing factor 3B subunit 3. Showing 1 copy in chain W [auth 3].

PF04046
Domain description: PSP
Occurring in:
  1. Splicing factor 3B subunit 2
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF04046 (PSP) in Splicing factor 3B subunit 2. Showing 1 copy in chain IA [auth 2].

PF04037
Domain description: Domain of unknown function (DUF382)
Occurring in:
  1. Splicing factor 3B subunit 2
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF04037 (Domain of unknown function (DUF382) ) in Splicing factor 3B subunit 2. Showing 1 copy in chain IA [auth 2].

PF02037
Domain description: SAP domain
Occurring in:
  1. Splicing factor 3B subunit 2
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF02037 (SAP domain) in Splicing factor 3B subunit 2. Showing 1 copy in chain IA [auth 2] (this domain is out of the observed residue ranges!).

PF22646
Domain description: PPP2R1A-like HEAT repeat
Occurring in:
  1. Splicing factor 3B subunit 1
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF22646 (PPP2R1A-like HEAT repeat) in Splicing factor 3B subunit 1. Showing 1 copy in chain V [auth 1].

PF08920
Domain description: Splicing factor 3B subunit 1
Occurring in:
  1. Splicing factor 3B subunit 1
The deposited structure of PDB entry 8i0p contains 1 copy of Pfam domain PF08920 (Splicing factor 3B subunit 1) in Splicing factor 3B subunit 1. Showing 1 copy in chain V [auth 1].

Rfam RNA families (Rfam)
RF00020
Domain description: U5 spliceosomal RNA
Occurring in:
  1. U5 snRNA

RF00026
Domain description: U6 spliceosomal RNA
Occurring in:
  1. U6 snRNA

RF00004
Domain description: U2 spliceosomal RNA
Occurring in:
  1. U2 snRNA

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