› 8i4h

Electron Microscopy
3.81Å resolution

Omicron spike variant BA.1 with Bn03

Released:
DOI: 10.2210/pdb8i4h/pdb
PDB entry 8i4h coloured by chain, front view.
PDB entry 8i4h coloured by chain, side view.
PDB entry 8i4h coloured by chain, top view.
Source organisms:
Primary publication:
Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants.
Hao A, Song W, Li C, Zhang X, Tu C, Wang X, Wang P, Wu Y, Ying T, Sun L
OpenAccess logo Signal Transduct Target Ther 8 269 (2023)
PMID: 37422451
Related structures: EMD-35173

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-272939 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Spike glycoprotein Chain: A
Molecule details ›
Chain: A
Length: 1285 amino acids
Theoretical weight: 142.51 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-212, 214-1208; Coverage: 94%)
Gene names: 2, S
Sequence domains:
Bn03 Chain: B
Molecule details ›
Chain: B
Length: 258 amino acids
Theoretical weight: 27.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.81Å
Relevant EMDB volumes: EMD-35173
Expression system: Homo sapiens

Quick links

Citations

1 review citation

Therapeutic nanobodies against SARS-CoV-2 and other pathogenic human coronaviruses.
Yang et al. (2024)
6 other articles