› › Structure analysis

Cryo-EM structure of 5-subunit Smc5/6 hinge region

Electron Microscopy
6.73Å resolution
PDB entry 8i4u coloured by chain, front view.
PDB entry 8i4u coloured by chain, side view.
PDB entry 8i4u coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Assembly composition:
hetero trimer (preferred)
Entry contents: 3 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero trimer
Accessible surface area: 67997.21 Å2
Buried surface area: 8637.47 Å2
Dissociation area: 1,558.48 Å2
Dissociation energy (ΔGdiss): 4.21 kcal/mol
Dissociation entropy (TΔSdiss): 14.03 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-243760

Macromolecules

Structural maintenance of chromosomes protein 5
Chain: A
Length: 1093 amino acids
Theoretical weight: 126.24 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q08204 (Residues: 1-1093; Coverage: 100%)
Gene names: SMC5, YOL034W
Pfam: RecF/RecN/SMC N terminal domain
Structural maintenance of chromosomes protein 5 in PDB entry 8i4u, assembly 1, front view.
Structural maintenance of chromosomes protein 5 in PDB entry 8i4u, assembly 1, side view.
Structural maintenance of chromosomes protein 5 in PDB entry 8i4u, assembly 1, top view.
Molecule details ›

Search similar proteins

Structural maintenance of chromosomes protein 6
Chain: B
Length: 1114 amino acids
Theoretical weight: 128.2 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q12749 (Residues: 1-1114; Coverage: 100%)
Gene names: L3502.2, RHC18, SMC6, YLR383W
Pfam: AAA domain
Structural maintenance of chromosomes protein 6 in PDB entry 8i4u, assembly 1, front view.
Structural maintenance of chromosomes protein 6 in PDB entry 8i4u, assembly 1, side view.
Structural maintenance of chromosomes protein 6 in PDB entry 8i4u, assembly 1, top view.
Molecule details ›

Search similar proteins

E3 SUMO-protein ligase MMS21
Chain: C
Length: 267 amino acids
Theoretical weight: 30.39 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P38632 (Residues: 1-267; Coverage: 100%)
Gene names: MMS21, NSE2, YEL019C
Pfam:
E3 SUMO-protein ligase MMS21 in PDB entry 8i4u, assembly 1, front view.
E3 SUMO-protein ligase MMS21 in PDB entry 8i4u, assembly 1, side view.
E3 SUMO-protein ligase MMS21 in PDB entry 8i4u, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links