› 8i6q

Electron Microscopy
4.23Å resolution

Cryo-EM structure of Pseudomonas aeruginosa FtsE(WT)X complex in peptidisc

Released:
DOI: 10.2210/pdb8i6q/pdb
PDB entry 8i6q coloured by chain, front view.
PDB entry 8i6q coloured by chain, side view.
PDB entry 8i6q coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site.
Xu X, Li J, Chua WZ, Pages MA, Shi J, Hermoso JA, Bernhardt T, Sham LT, Luo M
OpenAccess logo Proc Natl Acad Sci U S A 120 e2301897120 (2023)
PMID: 37186861
Related structures: EMD-35203

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-217140 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cell division protein FtsX Chains: A, C
Molecule details ›
Chains: A, C
Length: 335 amino acids
Theoretical weight: 36.96 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A072ZG76 (Residues: 1-335; Coverage: 100%)
Gene names: ALP65_03531, CAZ10_33465, DT376_11295, GNQ48_08045, GUL26_18695, IPC1295_09895, IPC737_09890, L4V69_05245, PAERUG_P19_London_7_VIM_2_05_10_00981, ftsX
Sequence domains:
Cell division ATP-binding protein FtsE Chains: B, D
Molecule details ›
Chains: B, D
Length: 223 amino acids
Theoretical weight: 24.65 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A069QBX1 (Residues: 1-223; Coverage: 100%)
Gene names: CAZ10_33460, DT376_11290, GNQ48_08050, GUL26_18700, IPC1295_09900, IPC737_09885, L4V69_05240, ftsE
Sequence domains: ABC transporter

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.23Å
Relevant EMDB volumes: EMD-35203
Expression system: Escherichia coli

Quick links

Citations

6 citation in other articles

Regulation of the cell division hydrolase RipC by the FtsEX system in Mycobacterium tuberculosis.
Li et al. (2023)
5 more