› 8i8e

Electron Microscopy
2.63Å resolution

Acyl-ACP synthetase structure bound to C18:1-ACP

Released:
DOI: 10.2210/pdb8i8e/pdb
PDB entry 8i8e coloured by chain, front view.
PDB entry 8i8e coloured by chain, side view.
PDB entry 8i8e coloured by chain, top view.
Source organisms:
Primary publication:
Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase.
Huang H, Wang C, Chang S, Cui T, Xu Y, Huang M, Zhang H, Zhou C, Zhang X, Feng Y
Nat Struct Mol Biol (2025)
PMID: 39794554
Related structures: EMD-35249

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-284555 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Acyl carrier protein Chains: a, b, c, d, e, f
Molecule details ›
Chains: a, b, c, d, e, f
Length: 78 amino acids
Theoretical weight: 8.99 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A6A8 (Residues: 1-78; Coverage: 100%)
Gene names: JW1080, acpP, b1094
Sequence domains: Phosphopantetheine attachment site
Acyl-acyl carrier protein synthetase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 533 amino acids
Theoretical weight: 60.5 KDa
Source organism: Vibrio harveyi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00IB3 (Residues: 1-533; Coverage: 100%)
Gene name: aasS
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand AMP 6 x AMP
Ligand OLA 6 x OLA
1 modified residue:
Ligand 4HH 6 x 4HH

Experiments and Validation Details

Entry percentile scores
Resolution: 2.63Å
Relevant EMDB volumes: EMD-35249
Expression system: Escherichia coli

Quick links