› 8i9m

Electron Microscopy
5.19Å resolution

The RAGE and HMGB1 complex

Released:
DOI: 10.2210/pdb8i9m/pdb
PDB entry 8i9m coloured by chain, front view.
PDB entry 8i9m coloured by chain, side view.
PDB entry 8i9m coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Han CW, Kim HJ
Related structures: EMD-35276

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-272480 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
High mobility group protein B1 Chain: A
Molecule details ›
Chain: A
Length: 75 amino acids
Theoretical weight: 8.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09429 (Residues: 89-163; Coverage: 35%)
Gene names: HMG1, HMGB1
Sequence domains: HMG (high mobility group) box
Advanced glycosylation end product-specific receptor Chain: B
Molecule details ›
Chain: B
Length: 211 amino acids
Theoretical weight: 23.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15109 (Residues: 23-233; Coverage: 55%)
Gene names: AGER, RAGE
Sequence domains: CD80-like C2-set immunoglobulin domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 5.19Å
Relevant EMDB volumes: EMD-35276
Expression system: Escherichia coli

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