› 8idn

Electron Microscopy
3.35Å resolution

Cryo-EM structure of RBD/E77-Fab complex

Released:
DOI: 10.2210/pdb8idn/pdb
PDB entry 8idn coloured by chain, front view.
PDB entry 8idn coloured by chain, side view.
PDB entry 8idn coloured by chain, top view.
Source organisms:
Primary publication:
The structure of the RBD-E77 Fab complex reveals neutralization and immune escape of SARS-CoV-2.
Zhang Z, Li X, Xue Y, Yang B, Jia Y, Liu S, Lu D
Acta Crystallogr D Struct Biol 79 746-757 (2023)
PMID: 37428848
Related structures: EMD-35369

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-535153 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 23.28 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 332-531; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
E77 Fab heavy chain Chain: H
Molecule details ›
Chain: H
Length: 239 amino acids
Theoretical weight: 25.56 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
E77 Fab light chain Chain: L
Molecule details ›
Chain: L
Length: 233 amino acids
Theoretical weight: 24.81 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.35Å
Relevant EMDB volumes: EMD-35369
Expression system: Homo sapiens

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