› 8ij5

Electron Microscopy
3Å resolution

Cryo-EM structure of Integrin AVB3

Released:
DOI: 10.2210/pdb8ij5/pdb
PDB entry 8ij5 coloured by chain, front view.
PDB entry 8ij5 coloured by chain, side view.
PDB entry 8ij5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Xi Z, Cang W, Yuanzhu G
Related structures: EMD-35465

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138434 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin beta-3 Chain: B
Molecule details ›
Chain: B
Length: 467 amino acids
Theoretical weight: 51.58 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P05106 (Residues: 31-497; Coverage: 61%)
Gene names: GP3A, ITGB3
Sequence domains:
Integrin alpha-V heavy chain Chain: E
Molecule details ›
Chain: E
Length: 593 amino acids
Theoretical weight: 65.27 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P06756 (Residues: 31-623; Coverage: 58%)
Gene names: ITGAV, MSK8, VNRA, VTNR
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3Å
Relevant EMDB volumes: EMD-35465
Expression system: Homo sapiens

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