› 8ikj

Electron Microscopy
3.2Å resolution

Cryo-EM structure of the inactive CD97

Released:
DOI: 10.2210/pdb8ikj/pdb
PDB entry 8ikj coloured by chain, front view.
PDB entry 8ikj coloured by chain, side view.
PDB entry 8ikj coloured by chain, top view.
Source organisms:
Primary publication:
Conformational transitions and activation of the adhesion receptor CD97.
Mao C, Zhao RJ, Dong YJ, Gao M, Chen LN, Zhang C, Xiao P, Guo J, Qin J, Shen DD, Ji SY, Zang SK, Zhang H, Wang WW, Shen Q, Sun JP, Zhang Y
Mol Cell (2024)
PMID: 38215752
Related structures: EMD-35514

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-239923 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adhesion G protein-coupled receptor E5 subunit alpha; Soluble cytochrome b562 Chain: R
Molecule details ›
Chain: R
Length: 655 amino acids
Theoretical weight: 72.55 KDa
Source organisms: Expression system: Fusarium sinicum
UniProt:
  • Canonical: P48960 (Residues: 257-720, 734-808; Coverage: 66%)
  • Canonical: P0ABE7 (Residues: 21-127; Coverage: 99%)
Gene names: ADGRE5, CD97, cybC
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-35514
Expression system: Fusarium sinicum

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