8ipk

X-ray diffraction
1.9Å resolution

The structure of human mitochondrial methyltransferase METTL15 with SAM

Released:
Model geometry
Fit model/data

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-269873 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
12S rRNA N(4)-cytidine methyltransferase METTL15 Chain: A
Molecule details ›
Chain: A
Length: 338 amino acids
Theoretical weight: 37.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: A6NJ78 (Residues: 70-407; Coverage: 83%)
Gene names: METT5D1, METTL15
Sequence domains: MraW methylase family

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P3121
Unit cell:
a: 70.506Å b: 70.506Å c: 134.674Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.184 0.182 0.221
Expression system: Escherichia coli