› 8ipp

X-ray diffraction
2.01Å resolution

Crystal structure of the complex between an ankyrin and a parallel G-quadruplex

Released:
DOI: 10.2210/pdb8ipp/pdb
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PDB entry 8ipp coloured by chain, front view.
PDB entry 8ipp coloured by chain, side view.
PDB entry 8ipp coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Structural Basis for Parallel G-Quadruplex Recognition by an Ankyrin Protein.
Ngo KH, Liew CW, Heddi B, Phan AT
J Am Chem Soc 146 13709-13713 (2024)
PMID: 38738955

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-247597 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
DARPin protein 2E4 Chain: B
Molecule details ›
Chain: B
Length: 136 amino acids
Theoretical weight: 14.86 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
93del-T12 Chain: A
Molecule details ›
Chain: A
Length: 16 nucleotides
Theoretical weight: 5.13 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand K 3 x K
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P21212
Unit cell:
a: 76.759Å b: 83.587Å c: 31.858Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.211 0.224
Expression systems:
  • Escherichia coli
  • Not provided

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