Function and Biology Details
Reactions catalysed:
4 ferrocytochrome c + O(2) + 8 H(+)(Side 1) = 4 ferricytochrome c + 4 H(2)O(Side 2)
NADH + ubiquinone + 5 H(+)(Side 1) = NAD(+) + ubiquinol + 4 H(+)(Side 2)
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero 103-mer (preferred)
PDBe Complex ID:
PDB-CPX-240371 (preferred)
Entry contents:
90 distinct polypeptide molecules
Macromolecules (90 distinct):
Cytochrome c oxidase subunit 1
Molecule details ›
Chain: C1
Length: 495 amino acids
Theoretical weight: 55.76 KDa
Source organism: Euglena gracilis
UniProt:
Sequence domains: Cytochrome C and Quinol oxidase polypeptide I
Length: 495 amino acids
Theoretical weight: 55.76 KDa
Source organism: Euglena gracilis
UniProt:
- Canonical:
Q34463 (Residues: 1-495; Coverage: 100%)
Sequence domains: Cytochrome C and Quinol oxidase polypeptide I
Cytochrome c oxidase subunit 2
Molecule details ›
Chain: C2
Length: 196 amino acids
Theoretical weight: 22.44 KDa
Source organism: Euglena gracilis
UniProt:
Sequence domains:
Length: 196 amino acids
Theoretical weight: 22.44 KDa
Source organism: Euglena gracilis
UniProt:
- Canonical: Q9XN19 (Residues: 1-196; Coverage: 100%)
Sequence domains:
Putative NADH dehydrogenase subunit 6
Molecule details ›
Chain: C3
Length: 161 amino acids
Theoretical weight: 19.41 KDa
Source organism: Euglena gracilis
UniProt:
Length: 161 amino acids
Theoretical weight: 19.41 KDa
Source organism: Euglena gracilis
UniProt:
- Canonical: Q9XN18 (Residues: 1-161; Coverage: 100%)
NADH-ubiquinone oxidoreductase chain 4
Molecule details ›
Chain: N4
Length: 478 amino acids
Theoretical weight: 56.42 KDa
Source organism: Euglena gracilis
UniProt:
Sequence domains: Proton-conducting membrane transporter
Length: 478 amino acids
Theoretical weight: 56.42 KDa
Source organism: Euglena gracilis
UniProt:
- Canonical: A0A0S2YRV6 (Residues: 1-478; Coverage: 100%)
Sequence domains: Proton-conducting membrane transporter
Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial
Molecule details ›
Chains: QB, Qb
Length: 474 amino acids
Theoretical weight: 51.13 KDa
Source organism: Euglena gracilis
UniProt:
Length: 474 amino acids
Theoretical weight: 51.13 KDa
Source organism: Euglena gracilis
UniProt:
- Canonical: P43265 (Residues: 1-474; Coverage: 100%)
Cytochrome b
Molecule details ›
Chains: QC, Qc
Length: 368 amino acids
Theoretical weight: 42.48 KDa
Source organism: Euglena gracilis
UniProt:
Sequence domains:
Length: 368 amino acids
Theoretical weight: 42.48 KDa
Source organism: Euglena gracilis
UniProt:
- Canonical: A0A0S2YRT7 (Residues: 13-380; Coverage: 97%)
Sequence domains:
Cytochrome c1, heme protein
Molecule details ›
Chains: QD, Qd
Length: 243 amino acids
Theoretical weight: 27.89 KDa
Source organism: Euglena gracilis
UniProt:
Length: 243 amino acids
Theoretical weight: 27.89 KDa
Source organism: Euglena gracilis
UniProt:
- Canonical: P20114 (Residues: 1-243; Coverage: 100%)
Ubiquinol-cytochrome-C reductase complex subunit IX, mitochondrial
Molecule details ›
Chains: QK, Qk
Length: 100 amino acids
Theoretical weight: 11.3 KDa
Source organism: Euglena gracilis
UniProt:
Length: 100 amino acids
Theoretical weight: 11.3 KDa
Source organism: Euglena gracilis
UniProt:
- Canonical: P43266 (Residues: 1-100; Coverage: 100%)
