› 8izm

Electron Microscopy
3.01Å resolution

Structure of the Mumps Virus L Protein (state2) Bound by Phosphoprotein Tetramer

Released:
DOI: 10.2210/pdb8izm/pdb
PDB entry 8izm coloured by chain, front view.
PDB entry 8izm coloured by chain, side view.
PDB entry 8izm coloured by chain, top view.
Source organism: Mumps virus strain Jeryl Lynn
Entry authors: Li TH, Shen QT
Related structures: EMD-35865

Function and Biology Details

Reactions catalysed: 
(1a) S-adenosyl-L-methionine + G(5')pppAACA-[mRNA] = S-adenosyl-L-homocysteine + G(5')pppAmACA-[mRNA]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
(1a) (5')pppAACA-[mRNA] + (protein L)-L-histidine = diphosphate + (protein L)-L-histidyl-(5')phosphonato-AACA-[mRNA] + H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-275406 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Phosphoprotein Chains: B, C, D, E
Molecule details ›
Chains: B, C, D, E
Length: 391 amino acids
Theoretical weight: 41.65 KDa
Source organism: Mumps virus strain Jeryl Lynn
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9J4L6 (Residues: 1-391; Coverage: 100%)
Gene name: P
Sequence domains: Paramyxovirus P/V phosphoprotein C-terminal
RNA-directed RNA polymerase L Chain: A
Molecule details ›
Chain: A
Length: 2261 amino acids
Theoretical weight: 256.83 KDa
Source organism: Mumps virus strain Jeryl Lynn
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9J4L0 (Residues: 1-2261; Coverage: 100%)
Gene name: L
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.01Å
Relevant EMDB volumes: EMD-35865
Expression system: Spodoptera frugiperda

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