› 8izp

Electron Microscopy
3.31Å resolution

Multidrug resistance-associated protein 3

Released:
DOI: 10.2210/pdb8izp/pdb
PDB entry 8izp coloured by chain, front view.
PDB entry 8izp coloured by chain, side view.
PDB entry 8izp coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yun CH, Gao HM
Related structures: EMD-35867

Function and Biology Details

Reactions catalysed: 
ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2)
ATP + H(2)O + glutathione-S-conjugate(Side 1) = ADP + phosphate + glutathione-S-conjugate(Side 2)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-217250 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-binding cassette sub-family C member 3 Chain: A
Molecule details ›
Chain: A
Length: 1571 amino acids
Theoretical weight: 174.55 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O15438 (Residues: 1-1527; Coverage: 100%)
Gene names: ABCC3, CMOAT2, MLP2, MRP3
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.31Å
Relevant EMDB volumes: EMD-35867
Expression system: Homo sapiens

Quick links