Function and Biology

The cryo-EM structure of Fe3+ induced alpha-syn fibril.

Source organism: Homo sapiens
Biochemical function: ATPase binding
Biological process: regulation of lysosome organization
Cellular component: late endosome membrane

Sequence families

Pfam Protein families (Pfam)
PF07092
Domain description: TM106 protein C-terminal domain
Occurring in:
  1. Transmembrane protein 106B
The deposited structure of PDB entry 8j7n contains 3 copies of Pfam domain PF07092 (TM106 protein C-terminal domain) in Transmembrane protein 106B. Showing 1 copy in chain A.

PF21002
Domain description: Transmembrane protein 106 N-terminal region
Occurring in:
  1. Transmembrane protein 106B
The deposited structure of PDB entry 8j7n contains 3 copies of Pfam domain PF21002 (Transmembrane protein 106 N-terminal region) in Transmembrane protein 106B. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).