8j8r

Electron Microscopy
2.9Å resolution

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-272403 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Beta-arrestin-2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 420 amino acids
Theoretical weight: 47.22 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P32120 (Residues: 1-420; Coverage: 100%)
Gene name: ARRB2
Sequence domains:
Fab30 Heavy Chain Chains: D, H, M
Molecule details ›
Chains: D, H, M
Length: 237 amino acids
Theoretical weight: 25.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Fab30 Light Chain Chains: E, L, N
Molecule details ›
Chains: E, L, N
Length: 215 amino acids
Theoretical weight: 23.44 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Muscarinic acetylcholine receptor M2 Chains: G, U, V
Molecule details ›
Chains: G, U, V
Length: 18 amino acids
Theoretical weight: 2.36 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P08172 (Residues: 300-317; Coverage: 4%)
Gene name: CHRM2

Ligands and Environments

No bound ligands
2 modified residues:

Experiments and Validation Details

Entry percentile scores
Resolution: 2.9Å
Relevant EMDB volumes: EMD-36078
Expression systems:
  • Escherichia coli
  • Not provided