8jhi

Electron Microscopy
3.2Å resolution

FZD3-Gs complex

Released:
Source organism: Homo sapiens
Related structures: EMD-36266

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-274015 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Chain: A
Molecule details ›
Chain: A
Length: 248 amino acids
Theoretical weight: 28.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
Molecule details ›
Chain: B
Length: 337 amino acids
Theoretical weight: 37.07 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: C
Nb35 Chain: N
Frizzled-3 Chain: R

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-36266
Expression systems:
  • Escherichia coli
  • Trichoplusia ni
  • Spodoptera frugiperda