8jj2

Electron Microscopy
4.3Å resolution

Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab2G7 in one fab conformation

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-274450 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (5 distinct):
Glutamate receptor ionotropic, NMDA 2A Chains: A, C
Molecule details ›
Chains: A, C
Length: 841 amino acids
Theoretical weight: 94.14 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Glutamate receptor ionotropic, NMDA 1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 847 amino acids
Theoretical weight: 95.24 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Fab2G7 Heavy Chain Chain: E
Fab2G7 Light Chain Chain: F

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.3Å
Relevant EMDB volumes: EMD-36338
Expression system: Homo sapiens