Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144194 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (6 distinct):
Processed angiotensin-converting enzyme 2
Molecule details ›
Chain: A
Length: 639 amino acids
Theoretical weight: 73.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Angiotensin-converting enzyme
Length: 639 amino acids
Theoretical weight: 73.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9BYF1 (Residues: 1-615; Coverage: 76%)
Sequence domains: Angiotensin-converting enzyme
Spike glycoprotein
Molecule details ›
Chain: B
Length: 1251 amino acids
Theoretical weight: 138.62 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 1251 amino acids
Theoretical weight: 138.62 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
- Canonical: P0DTC2 (Residues: 14-1211; Coverage: 95%)
Sequence domains:
Ligands and Environments
No modified residues
